Brain Mysteries
Recent News |  Archives |  Tags |  Newsletter |  Message Board/Forum |  About |  Links |  Subscribe to BrainMysteries.com RSS Feed Subscribe


More Articles
Improvements in fuel cell designImprovements in fuel cell design

Rediscovering Venus to find faraway earthsRediscovering Venus to find faraway earths

Archaeologists discover bronze remains of Iron Age chariotArchaeologists discover bronze remains of Iron Age chariot

Researchers resolve the Karakoram glacier anomaly, a cold case of climate scienceResearchers resolve the Karakoram glacier anomaly, a cold case of climate science

Fish tale: New study evaluates antibiotic content in farm-raised fishFish tale: New study evaluates antibiotic content in farm-raised fish

New 3-D display technology promises greater energy efficiencyNew 3-D display technology promises greater energy efficiency

Researchers break nano barrier to engineer the first protein microfiberResearchers break nano barrier to engineer the first protein microfiber

Magnetic mirrors enable new technologies by reflecting light in uncanny waysMagnetic mirrors enable new technologies by reflecting light in uncanny ways

Structure of an iron-transport protein revealedStructure of an iron-transport protein revealed

First step: From human cells to tissue-engineered esophagusFirst step: From human cells to tissue-engineered esophagus

Autophagy helps fast track stem cell activationAutophagy helps fast track stem cell activation

Myelin vital for learning new practical skillsMyelin vital for learning new practical skills

Spiders: Survival of the fittest groupSpiders: Survival of the fittest group

More physical activity improved school performanceMore physical activity improved school performance

Around the world in 400,000 years: The journey of the red foxAround the world in 400,000 years: The journey of the red fox

Engineering new vehicle powertrainsEngineering new vehicle powertrains

Active aging is much more than exerciseActive aging is much more than exercise

Study: New device can slow, reverse heart failureStudy: New device can slow, reverse heart failure

Are the world's religions ready for ET?Are the world's religions ready for ET?

Gut bacteria, artificial sweeteners and glucose intoleranceGut bacteria, artificial sweeteners and glucose intolerance

Recreating the stripe patterns found in animals by engineering synthetic gene networksRecreating the stripe patterns found in animals by engineering synthetic gene networks

Laying the groundwork for data-driven scienceLaying the groundwork for data-driven science

Hold on, tiger momHold on, tiger mom

Nature's designs inspire research into new light-based technologiesNature's designs inspire research into new light-based technologies

Missing piece found to help solve concussion puzzleMissing piece found to help solve concussion puzzle

Biologists delay the aging process by 'remote control'Biologists delay the aging process by 'remote control'

Geography matters: Model predicts how local 'shocks' influence U.S. economyGeography matters: Model predicts how local 'shocks' influence U.S. economy

Identified for the first time what kind of explosive has been used after the detonationIdentified for the first time what kind of explosive has been used after the detonation

Copied from nature: Detecting software errors via genetic algorithmsCopied from nature: Detecting software errors via genetic algorithms

Placebos work -- even without deception (12/24/2010)

Tags:
placebo

For most of us, the "placebo effect" is synonymous with the power of positive thinking; it works because you believe you're taking a real drug. But a new study rattles this assumption.

Researchers at Harvard Medical School's Osher Research Center and Beth Israel Deaconess Medical Center (BIDMC) have found that placebos work even when administered without the seemingly requisite deception.

The study is published December 22 in PLoS ONE.

Placebos-or dummy pills-are typically used in clinical trials as controls for potential new medications. Even though they contain no active ingredients, patients often respond to them. In fact, data on placebos is so compelling that many American physicians (one study estimates 50 percent) secretly give placebos to unsuspecting patients.

Because such "deception" is ethically questionable, HMS associate professor of medicine Ted Kaptchuk teamed up with colleagues at BIDMC to explore whether or not the power of placebos can be harnessed honestly and respectfully.

To do this, 80 patients suffering from irritable bowel syndrome (IBS) were divided into two groups: one group, the controls, received no treatment, while the other group received a regimen of placebos-honestly described as "like sugar pills"-which they were instructed to take twice daily.

"Not only did we make it absolutely clear that these pills had no active ingredient and were made from inert substances, but we actually had 'placebo' printed on the bottle," says Kaptchuk. "We told the patients that they didn't have to even believe in the placebo effect. Just take the pills."

For a three-week period, the patients were monitored. By the end of the trial, nearly twice as many patients treated with the placebo reported adequate symptom relief as compared to the control group (59 percent vs. 35 percent). Also, on other outcome measures, patients taking the placebo doubled their rates of improvement to a degree roughly equivalent to the effects of the most powerful IBS medications.

"I didn't think it would work," says senior author Anthony Lembo, HMS associate professor of medicine at BIDMC and an expert on IBS. "I felt awkward asking patients to literally take a placebo. But to my surprise, it seemed to work for many of them."

The authors caution that this study is small and limited in scope and simply opens the door to the notion that placebos are effective even for the fully informed patient-a hypothesis that will need to be confirmed in larger trials.

"Nevertheless," says Kaptchuk, "these findings suggest that rather than mere positive thinking, there may be significant benefit to the very performance of medical ritual. I'm excited about studying this further. Placebo may work even if patients knows it is a placebo."

Note: This story has been adapted from a news release issued by the Harvard Medical School

Post Comments:

Search
New Articles
Psychologists awarded 250,000 to delve inside the minds of contemporary dancers

Reminiscing can help boost mental performance

Receiving gossip about others promotes self-reflection and growth

Brain simulation raises questions

Researchers record sight neurons in jumping spider brain

Mathematical model shows how the brain remains stable during learning

Male and female brains aren't equal when it comes to fat

Identifying hidden minds in impaired consciousnessIdentifying hidden minds in impaired consciousness

Scientists find 'hidden brain signatures' of consciousness in vegetative state patientsScientists find 'hidden brain signatures' of consciousness in vegetative state patients

Brain's compass relies on geometric relationships, say researchersBrain's compass relies on geometric relationships, say researchers

Oh brother! Having a sibling makes boys selfless

New look at neuroscience draws experts to ASU

Brain surgery through the cheekBrain surgery through the cheek

Change your walking style, change your mood

Risking your life without a second thought



Archives
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007


Science Friends
Agricultural Science
Astronomy News
Sports Tech
Biology News
Biomimicry Science
Chemistry News
Tissue Engineering
Cancer Research
Cybernetics Research
Electonics Research
Forensics Report
Fossil News
Genetic Archaeology
Genetics News
Geology News
Microbiology Research
Nanotech News
Parenting News
Physics News


  Archives |  Submit News |  Advertise With Us |  Contact Us |  Links
Use of this site constitutes acceptance of our Terms of Service and Privacy Policy. All contents © 2000 - 2015 Web Doodle, LLC. All rights reserved.